RESUMO
Background: Anemia and thrombocytopenia are common features in patients with Systemic Lupus Erythematosus (SLE). However, erythroid aplasia and amegakaryocytosis as the main physiopathological causes without other associated disorders have been rarely described. Case report: We report a 29 y/o female with SLE presenting with severe anemia and thrombocytopenia due to a bone marrow immunological blockage. The patient, who initially refused transfusions, was successfully treated and had a very fast hematological response to steroids, immunoglobulin, plasma exchange, eltrombopag, and rituximab. Discussion: This is an unusual case and it is possible that in this kind of patients plasma exchange associated with immunosuppressant therapy may lead to a faster, more effective, and sustained recovery of the hematological disorders. (AU)
